Paraffin-snittat material har grans

Paraffin-snittat material har granskats och tidigare avgiven fryssnitts-diagnos bekräftas, Det ses således bindväv, kärl och nerver, samt inflammation och ganska utbredd växt av atypiska celler som växer enskilt och i rader. Inget signetrings-cells-utseende. Immunhistokemisk karakterisering visar stark positivitet för CK7 i tumör-cellerna. En mindre andel är också starkt positiva får CK20. Färgningar för MUC-1 och MUC-2 är också positiva liksom CDX2 där den sistnämnda är mycket svag och heterogent positiv i tumör-cells-kärnorna. Färgningar för PSA och PSAP är negativa, samt TTFl. Uttrycket av SMAD4 är bevarat.

Resultat (engelska) 1:

Paraffin-sectioned material has been reviewed and previously ceded fryssnitts-diagnosis is confirmed, it will be seen therefore, connective tissue, blood vessels and nerves, as well as inflammation and quite widespread plant of atypical cells that grow individually and in rows. No signetrings-cell appearance. Immunohistochemical characterization shows strong positivity for CK7 in tumor cells. A smaller percentage is also strongly positive, CK20. Colorings of MUC-1 and MUC-2 is also positive as CDX2, where the latter is very weak and heterogeneous positive in tumor cell nuclei. Stainings for PSA and PSAP are negative, and TTFl. The expression of SMAD4 is preserved.

Resultat (engelska) 2:

Paraffin-sectioned material has been reviewed and previously ceded fryssnitts diagnosis is confirmed, it is thus seen connective tissue, vessels and nerves, as well as inflammation and fairly widespread growth of atypical cells that grow individually and in rows. No signetrings cell appearance. Immunohistochemical characterization shows strong positivity for CK7 in tumor cells. A smaller proportion is also strongly positive must CK20. Stains for MUC-1 and MUC-2 is also positive as well as CDX2, the latter being very weak and heterogenous positive in tumor cell nuclei. Color Listings for PSA and PSAP are negative, and TTFl. The expression of Smad4 is preserved.

Resultat (engelska) 3:

the paraffin cut material has been reviewed and the previous heat fryssnitts diagnosis is confirmed, it is seen, therefore, connective tissue, vessels and nerves, and inflammation, and quite widespread growth of atypical cells growing individually and in rows. no signetrings cell appearance. immunohistochemical characterisation showed strong positivity for ck7 in tumor cells. a smaller proportion is also strongly positive may ck20. färgningar for muc - 1 and - 2 muc is also positive, as well as cdx2 where the latter is very weak and heterogeneous positive in tumor cell nuclei. färgningar for psa and psap is negative, and ttfl. the expression of smad4 is preserved.